- A new topical parasiticide for cats combines the active ingredient in Stronghold – selamectin – with sarolaner for broadened and extended spectrum of protection
- Company introduces first combination product building on its sarolaner platform in the $4.2 billion companion animal parasiticide market
Zoetis
Inc. (NYSE:ZTS) today announced that the European Commission has
granted the company a license for Stronghold® Plus
(selamectin/sarolaner), a topical combination of parasiticides that
treats ticks, fleas, ear mites, lice and gastrointestinal nematodes and
prevents heartworm disease in cats.
Veterinarians across the European Union now have a treatment choice that
leverages the benefits of sarolaner, a new innovation in the class of
isoxazolines, without sacrificing the broad spectrum protection, safety
or ease of use they expect.
”The approval of Stronghold Plus enables Zoetis to offer veterinarians a
new topical choice that treats the parasites commonly presenting a
threat to cats with one convenient monthly dose,” said Dr. Catherine
Knupp, Executive Vice President and President, Research and Development
at Zoetis. “For the first time, we have combined our new, versatile
parasiticide sarolaner with the active ingredient in Stronghold,
selamectin, resulting in the first approval of sarolaner for use in
cats. We see sarolaner as a promising platform for future product lines
and lifecycle innovations and are pleased with the positive data that
sarolaner and its combination continue to generate in studies.”
The market for companion animal parasitic medicines was valued at more
than $4.2 billion in 2015, with a compound annual growth rate of about
5% over the previous five years, according to Vetnosis1.
Domenico Otranto, Professor of Parasitology at The University of Bari in
Italy, who recently reviewed the product data of Stronghold Plus, said:
“A number of laboratory and field studies show the efficacy of the
single spot-on application of Stronghold Plus for at least one month.
Veterinarians in the European Union will now have a very effective
option for the treatment and control of four prominent species of ticks
commonly found on cats while maintaining proven efficacy against fleas,
GI worms, heartworms, ear mites and lice. Ultimately, pet owners and
practitioners have a new tool for improving the health and welfare of
cats.”
Dr. Michael Stegemann, Senior Director of Veterinary Research and
Development at Zoetis, said: “Stronghold Plus was entirely discovered
and developed by Zoetis scientists. It provides fast, sustained coverage
from the fleas and ticks most often found on cats. The combined action
of sarolaner and selamectin allows Stronghold Plus to kill four species
of ticks, and it lengthens the duration of protection against fleas to
five full weeks with no drop in efficacy at the end of the dosing period
-- all without sacrificing protection from other important internal and
external feline parasites. We’re excited to be able to bring this
innovation to veterinarians across the European Union.”
About Stronghold Plus product efficacy and safety:
The active substances in Stronghold Plus are selamectin and sarolaner, a
new combination of parasiticides. Selamectin has adulticidal, ovicidal
and larvicidal activity against fleas (Ctenocephalides spp).
Selamectin is also active against ear mites, lice, gastrointestinal
nematodes and prevents heartworm disease through its efficacy against Dirofilaria
immitis larvae. Sarolaner is a new acaricide and insecticide
belonging to the isoxazoline class: it is efficacious against ticks,
fleas and mites. The most common side effects of Stronghold Plus are
mild and transient pruritus at the application site. Mild to moderate
alopecia at the application site, erythema and drooling have been
uncommonly observed.
For more information about Stronghold Plus, click here.
About Zoetis
Zoetis
is the leading animal health company, dedicated to supporting its
customers and their businesses. Building on more than 60 years of
experience in animal health, Zoetis discovers, develops, manufactures
and markets veterinary vaccines and medicines, complemented by
diagnostic products and genetic tests and supported by a range of
services. Zoetis serves veterinarians, livestock producers and people
who raise and care for farm and companion animals with sales of its
products in more than 100 countries. In 2015, the company generated
annual revenue of $4.8 billion with approximately 9,000 employees. For
more information, visit
www.zoetis.com
.
DISCLOSURE NOTICES
Forward-Looking Statements: This press release contains
forward-looking statements, which reflect the current views of Zoetis
with respect to business plans or prospects, expectations regarding
products and other future events. These statements are not guarantees of
future performance or actions. Forward-looking statements are subject to
risks and uncertainties. If one or more of these risks or uncertainties
materialize, or if management's underlying assumptions prove to be
incorrect, actual results may differ materially from those contemplated
by a forward-looking statement. Forward-looking statements speak only as
of the date on which they are made. Zoetis expressly disclaims any
obligation to update or revise any forward-looking statement, whether as
a result of new information, future events or otherwise. A further list
and description of risks, uncertainties and other matters can be found
in our Annual Report on Form 10-K for the fiscal year ended December 31,
2015, including in the sections thereof captioned “Forward-Looking
Statements and Factors That May Affect Future Results” and “Item 1A.
Risk Factors,” in our Quarterly Reports on Form 10-Q and in our Current
Reports on Form 8-K. These filings and subsequent filings are available
online at
www.sec.gov
,
www.zoetis.com
,
or on request from Zoetis.
1 Vetnosis, Animal Health Service: Parasiticides
Report (Sept. 2016)
Zoetis Inc.
Media:
Anne-France Quentric, +32 227468311
anne-france.quentric@zoetis.com
or
Elinore White, 1-973-443-2835
elinore.y.white@zoetis.com
or
Investor:
Steve Frank, 1-973-822-7141
steve.frank@zoetis.com